Non Obstructive Azoospermia & Infertility

Two-thirds of azoospermic patients have non-obstructive azoospermia (NOA); the latter comprises up to 10% of infertile men overall.


Non Obstructive Azoospermia & Infertility

8 Mins
Updated on:
November 28, 2022
Male Infertility

Non Obstructive Azoospermia & Infertility

What is Non-Obstructive Azoospermia?


The lack of sperm cells in the ejaculate is known as azoospermia. It is divided into roughly 60% Non-obstructive Azoospermia (NOA) cases and 40% Obstructive Azoospermia cases (OA).Non-Obstructive Azoospermia (NOA) is a medical disorder in which spermatogenesis fails and a man is unable to make sperm. One of the most severe types of male infertility is this one.

Why does Non-Obstructive Azoospermia (NOA) occur?

NOA can occur for a variety of reasons:Hormonal imbalances: A disorder like NOA might be brought on by a hormonal deficit,issues with the genes and chromosomes.Testicular failure occurs when there is insufficient generation of sperm because there are insufficient germ cells in the testes.Maturation arrest is the absence of the final stages of the biological process known as spermatogenesis, which produces mature, motile sperm cells from early-stage cells.

What impact does this illness have on fertility?

Non-Obstructive Azoospermia is a condition in which a male is unable to produce sperm. The couple cannot conceive naturally as a result. The ICSI procedure allows doctors to remove healthy sperm from the testicles and utilise them to fertilise the egg following a combination of effective medical and surgical procedures.

How can this issue be identified?

The primary test for diagnosis is sperm analysis. In azoospermia, no sperm are present.To determine the causes and establish a treatment plan, additional investigations such hormone tests, chromosomal analysis (Karyotype and Yq microdeletions), and testicular ultrasonography are helpful.

Is NOA treatable in any way?

NOA is treated with a combination of surgical intervention and medication, including hormone therapy. The surgical methods for removing sperm from the testes directly are called TESE and Micro-TESE. ICSI fertility treatments will assist the couple in fertilising the eggs and obtaining the embryos once the sperm have been located.

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What our patients say


Is IVF hard on women’s bodies?

You will have much more hormones rushing through your body than usual as a result of all the hormone injections required during IVF. You might feel cranky, bloated, or even high libido as a result of that. It's not uncommon for women to gain a little weight. Hormone injections can affect your weight and also your hunger levels, along with changes in your emotions. Expect some changes to happen in your body and mind.

What is the cost of IVF treatment in Jananam?

Please check the pricing page.

Can I smoke during IVF treatment?

Smoking is a strict "No" if you’re looking to get pregnant. This is applicable to both men and women. Smoking has shown to have a big impact on the quality of the sperms and eggs and hence it’s advisable that you quit smoking if you’re planning to start a family.

What are the steps involved in IVF treatment?

A step by step guide to IVF treatment is conveyed in this video by our Medical Director – Dr Vani Sundarapandian..

Can I work and commute when undergoing IVF treatment?

This can only be suggested on a case to case basis depending on the various factors associated with the patient, such as age, medical condition, quality of eggs/sperms etc.

How do I prepare my body for IVF?

It's pretty doable. Begin taking prenatal supplements, keep a healthy weight, stop using drugs, drinking alcohol, or smoking, avoid serious infectious infections, which could cause a delay in treatment, and reduce consuming caffeine. Basically, maintain a healthy body by eating healthy and exercising regularly.

At what age is IVF most successful?

IVF success rates vary as it depends on multiple factors. One of these major factors is age. The success rate is almost 55-60% in women who are less than 35 years of age. The success rate goes down as the woman’s age increases. Ideally, the 20s and 30s are the best age to have a successful IVF.

How much of infertility is because of the man?

1/3 of infertility cases are attributable to men, 1/3 are attributable to women, and the rest are a combination of male and female factors or unexplained problems.

Do IVF hormones make you emotional?

Some women report having minimal to no reactions, while others say they are extremely anxious or even depressed. So be aware that you can experience an emotional response to the hormone changes; if you do, this is completely normal and okay.

How long should I try before deciding to see a fertility specialist?

If you’re unable to conceive after a year of actively trying to conceive, then you should consult a doctor.

Is IVF painful?

IVF shots are typically not too painful. Although there is a stinging feeling, it is not bothersome. The needles are too thin to cause any pain. When you inject the medication, you can invite your partner or perhaps a friend to stand by your side.

Can i drink alcohol during IVF treatment?

Drinking is strictly discouraged while prepping for IVF. Some studies have shown that alcohol may have an effect on the outcome of IVF.

Do IVF babies look different?

The woman becomes pregnant once the embryo is implanted in her uterus, and after a certain amount of time, she gives birth to her child. IVF children are just like any other children. In fact, it is impossible to tell an IVF baby apart from other kids unless you are told.

What is the cost of IVF treatment in Jananam?

To know more about the cost of IVF treatment, please visit our pricing page.

Are IVF babies always healthy?

Yes is the clear-cut response. With the use of in vitro fertilization (IVF), millions of healthy children have been born. There are no immediate or long-term risks to the child's health associated with the procedure. The method of conception is the main distinction between IVF babies and regular babies.

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