Recurrent Miscarriage

According to World Health Organization, 2.6 million babies are stillborn and an estimated 85 percent of miscarriages happen before the 12th week of pregnancy every year. In women between the age of 20 to 25, around 15%-16% pregnancies end in miscarriage, and amongst the 30 to 35 age group, miscarriage rate increases by 18 to 22%. However, at the age of 40, approximately 38% incidences of miscarriages are reported annually. While at 45 plus the chances of miscarriage in pregnancy increases by 70%.


Recurrent Miscarriage

8 Mins
Updated on:
February 21, 2023
Female Infertility

Recurrent Miscarriage

What is recurrent miscarriage?


A pregnancy loss that occurs repeatedly, two or more miscarriages is defined as RPL. After three consecutive miscarriages, a full physical checkup is advised.

What are the causes of RPL?

Most miscarriages happen at random when an unusually high number of chromosomes reaches the embryo.An abnormally high number of chromosomes in the embryo is the main cause of RPL.Recurrent miscarriages may also be exacerbated by uterine issues, immunological abnormalities, hormonal diseases (such as diabetes and thyroid issues), and uterine illnesses.The RPL may also be increased by additional factors like smoking, drinking alcohol and caffeine, being overweight, and being exposed to harmful goods.Uterine factors may involve:Inherited uterine abnormalities, such as a double uterus or a uterine septum.Big polyps and submucosal fibroids presentSyndrome Asherman (presence of scar tissue in the uterine cavity)Genetic Variables (Aneuploidy)A chromosomal abnormality in the embryo causes miscarriage.One partner sometimes carries a chromosome with a fragment transferred to another chromosome in relationships with a high rate of miscarriages. Translocation is the name of the procedure. Translocation patients frequently show no symptoms. There are certain chromosomal abnormalities in some of their eggs or sperm. A miscarriage may be indicated by the amount of genetic material an embryo receives, whether it is high or low.Hormonal disordersRPL can be detected by thyroid malfunction and uncontrolled blood sugar levels. Furthermore, even PCOS individuals have a higher risk of miscarriage due to changes in the endocrine profile.

Is there any effect of other health conditions on the risk of miscarriages?

Women who have health issues are more likely to experience numerous miscarriages.APS is an autoimmune condition known as antiphospholipid syndrome. In this, a person's immune system produces antibodies. These antibodies specifically target elements that are crucial to the process of blood coagulation. It has been discovered that APS is linked to RPL and foetal fatalities.A higher risk of miscarriage exists in women who have PCOS, commonly known as polycystic ovary syndrome.

How is Recurrent Pregnancy Loss assessed?

RPL can be initially evaluated by getting the whole patient history and performing a physical examination.A number of diagnostic procedures, such as blood testing and uterine examinations, are available. This examination looks for abnormalities or acquired conditions, such as polyps and fibroids, that could prevent the embryo from implanting properly.To determine and foretell the likelihood of a genetic defect in the embryo, the couple might also undergo a genetic compatibility test.

How to treat Recurrent Pregnancy Loss RPL?

Depending on the underlying cause of recurrent pregnancy loss, treatment is advised for women who experience it. A successful pregnancy is highly likely. A doctor should be consulted if a woman has had several miscarriages so they may determine the best course of action to take in order to lower the likelihood of future miscarriages.

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You will have much more hormones rushing through your body than usual as a result of all the hormone injections required during IVF. You might feel cranky, bloated, or even high libido as a result of that. It's not uncommon for women to gain a little weight. Hormone injections can affect your weight and also your hunger levels, along with changes in your emotions. Expect some changes to happen in your body and mind.

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Can I smoke during IVF treatment?

Smoking is a strict "No" if you’re looking to get pregnant. This is applicable to both men and women. Smoking has shown to have a big impact on the quality of the sperms and eggs and hence it’s advisable that you quit smoking if you’re planning to start a family.

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A step by step guide to IVF treatment is conveyed in this video by our Medical Director – Dr Vani Sundarapandian..

Can I work and commute when undergoing IVF treatment?

This can only be suggested on a case to case basis depending on the various factors associated with the patient, such as age, medical condition, quality of eggs/sperms etc.

At what age is IVF most successful?

IVF success rates vary as it depends on multiple factors. One of these major factors is age. The success rate is almost 55-60% in women who are less than 35 years of age. The success rate goes down as the woman’s age increases. Ideally, the 20s and 30s are the best age to have a successful IVF.

How do I prepare my body for IVF?

It's pretty doable. Begin taking prenatal supplements, keep a healthy weight, stop using drugs, drinking alcohol, or smoking, avoid serious infectious infections, which could cause a delay in treatment, and reduce consuming caffeine. Basically, maintain a healthy body by eating healthy and exercising regularly.

How much of infertility is because of the man?

1/3 of infertility cases are attributable to men, 1/3 are attributable to women, and the rest are a combination of male and female factors or unexplained problems.

Do IVF hormones make you emotional?

Some women report having minimal to no reactions, while others say they are extremely anxious or even depressed. So be aware that you can experience an emotional response to the hormone changes; if you do, this is completely normal and okay.

How long should I try before deciding to see a fertility specialist?

If you’re unable to conceive after a year of actively trying to conceive, then you should consult a doctor.

Is IVF painful?

IVF shots are typically not too painful. Although there is a stinging feeling, it is not bothersome. The needles are too thin to cause any pain. When you inject the medication, you can invite your partner or perhaps a friend to stand by your side.

Can i drink alcohol during IVF treatment?

Drinking is strictly discouraged while prepping for IVF. Some studies have shown that alcohol may have an effect on the outcome of IVF.

Do IVF babies look different?

The woman becomes pregnant once the embryo is implanted in her uterus, and after a certain amount of time, she gives birth to her child. IVF children are just like any other children. In fact, it is impossible to tell an IVF baby apart from other kids unless you are told.

What is the cost of IVF treatment in Jananam?

To know more about the cost of IVF treatment, please visit our pricing page.

Are IVF babies always healthy?

Yes is the clear-cut response. With the use of in vitro fertilization (IVF), millions of healthy children have been born. There are no immediate or long-term risks to the child's health associated with the procedure. The method of conception is the main distinction between IVF babies and regular babies.

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