Sperm DNA fragmentation testing

Infertility is on the rise. According to the United Nations, there was a worldwide average of 5 children per woman in 1950, but by 2020, that ratio had dropped to 2 children. Infertility affects 48 million couples and 186 million people globally, according to estimates.

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Sperm DNA fragmentation testing

6 Mins
Updated on:
February 21, 2023
Topic:
Male Infertility
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Sperm DNA fragmentation testing

When is testing for sperm DNA fragmentation (SDF) advised?

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It is advised that males with varicoceles undergo SDF testing (enlarged veins within the scrotum) Recurrent pregnancy loss, idiopathic or unexplained infertility, and IVF treatment failure abnormalities in the sperm's development and early cell death brought on by risk factors from a person's lifestyle that can be changed, such as heat exposure, smoking, exposure to toxins, and chemotherapeutics.

What are the various sperm DNA fragmentation testing procedures?

SDF testing can be divided into two categories: direct and indirect. In direct assays, dyes and probes are used to assess the degree of sperm DNA damage. Indirect assays, on the other hand, evaluate the DNA's sensitivity to denaturation, which occurs more frequently in fragmented DNA. The most popular techniques for measuring SDF are:Terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL)Sperm chromatin structure assay (SCSA)Sperm chromatin dispersion (SCD) test.

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Jananam Fertility has developed all of its medical services, procedures, patient care systems, and infrastructure with the patient in mind. We have the best success rates (pregnancies and live births) while maintaining the strictest safety requirements.

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IVF FAQ's

Is IVF hard on women’s bodies?

You will have much more hormones rushing through your body than usual as a result of all the hormone injections required during IVF. You might feel cranky, bloated, or even high libido as a result of that. It's not uncommon for women to gain a little weight. Hormone injections can affect your weight and also your hunger levels, along with changes in your emotions. Expect some changes to happen in your body and mind.

What is the cost of IVF treatment in Jananam?

Please check the pricing page.

Can I smoke during IVF treatment?

Smoking is a strict "No" if you’re looking to get pregnant. This is applicable to both men and women. Smoking has shown to have a big impact on the quality of the sperms and eggs and hence it’s advisable that you quit smoking if you’re planning to start a family.

What are the steps involved in IVF treatment?

A step by step guide to IVF treatment is conveyed in this video by our Medical Director – Dr Vani Sundarapandian..


Can I work and commute when undergoing IVF treatment?

This can only be suggested on a case to case basis depending on the various factors associated with the patient, such as age, medical condition, quality of eggs/sperms etc.

At what age is IVF most successful?

IVF success rates vary as it depends on multiple factors. One of these major factors is age. The success rate is almost 55-60% in women who are less than 35 years of age. The success rate goes down as the woman’s age increases. Ideally, the 20s and 30s are the best age to have a successful IVF.

How do I prepare my body for IVF?

It's pretty doable. Begin taking prenatal supplements, keep a healthy weight, stop using drugs, drinking alcohol, or smoking, avoid serious infectious infections, which could cause a delay in treatment, and reduce consuming caffeine. Basically, maintain a healthy body by eating healthy and exercising regularly.

How much of infertility is because of the man?

1/3 of infertility cases are attributable to men, 1/3 are attributable to women, and the rest are a combination of male and female factors or unexplained problems.

Do IVF hormones make you emotional?

Some women report having minimal to no reactions, while others say they are extremely anxious or even depressed. So be aware that you can experience an emotional response to the hormone changes; if you do, this is completely normal and okay.

How long should I try before deciding to see a fertility specialist?

If you’re unable to conceive after a year of actively trying to conceive, then you should consult a doctor.

Is IVF painful?

IVF shots are typically not too painful. Although there is a stinging feeling, it is not bothersome. The needles are too thin to cause any pain. When you inject the medication, you can invite your partner or perhaps a friend to stand by your side.

Can i drink alcohol during IVF treatment?

Drinking is strictly discouraged while prepping for IVF. Some studies have shown that alcohol may have an effect on the outcome of IVF.

Do IVF babies look different?

The woman becomes pregnant once the embryo is implanted in her uterus, and after a certain amount of time, she gives birth to her child. IVF children are just like any other children. In fact, it is impossible to tell an IVF baby apart from other kids unless you are told.

What is the cost of IVF treatment in Jananam?

To know more about the cost of IVF treatment, please visit our pricing page.

Are IVF babies always healthy?

Yes is the clear-cut response. With the use of in vitro fertilization (IVF), millions of healthy children have been born. There are no immediate or long-term risks to the child's health associated with the procedure. The method of conception is the main distinction between IVF babies and regular babies.

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