Recurrent Miscarriage

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Recurrent Miscarriage

According to World Health Organization, 2.6 million babies are stillborn and an estimated 85 percent of miscarriages happen before the 12th week of pregnancy every year. In women between the age of 20 to 25, around 15%-16% pregnancies end in miscarriage, and amongst the 30 to 35 age group, miscarriage rate increases by 18 to 22%. However, at the age of 40, approximately 38% incidences of miscarriages are reported annually. While at 45 plus the chances of miscarriage in pregnancy increases by 70%.

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Female Infertility Causes

Recurrent Miscarriage Causes

A pregnancy loss that occurs repeatedly, two or more miscarriages is defined as RPL. After three consecutive miscarriages, a full physical checkup is advised

Most miscarriages happen at random when an unusually high number of chromosomes reaches the embryo.An abnormally high number of chromosomes in the embryo is the main cause of RPL.Recurrent miscarriages may also be exacerbated by uterine issues, immunological abnormalities, hormonal diseases (such as diabetes and thyroid issues), and uterine illnesses.The RPL may also be increased by additional factors like smoking, drinking alcohol and caffeine, being overweight, and being exposed to harmful goods.Uterine factors may involve:Inherited uterine abnormalities, such as a double uterus or a uterine septum.Big polyps and submucosal fibroids presentSyndrome Asherman (presence of scar tissue in the uterine cavity)Genetic Variables (Aneuploidy)A chromosomal abnormality in the embryo causes miscarriage.One partner sometimes carries a chromosome with a fragment transferred to another chromosome in relationships with a high rate of miscarriages. Translocation is the name of the procedure. Translocation patients frequently show no symptoms. There are certain chromosomal abnormalities in some of their eggs or sperm. A miscarriage may be indicated by the amount of genetic material an embryo receives, whether it is high or low.Hormonal disordersRPL can be detected by thyroid malfunction and uncontrolled blood sugar levels. Furthermore, even PCOS individuals have a higher risk of miscarriage due to changes in the endocrine profile.

Women who have health issues are more likely to experience numerous miscarriages.APS is an autoimmune condition known as antiphospholipid syndrome. In this, a person's immune system produces antibodies. These antibodies specifically target elements that are crucial to the process of blood coagulation. It has been discovered that APS is linked to RPL and foetal fatalities.A higher risk of miscarriage exists in women who have PCOS, commonly known as polycystic ovary syndrome.

RPL can be initially evaluated by getting the whole patient history and performing a physical examination.A number of diagnostic procedures, such as blood testing and uterine examinations, are available. This examination looks for abnormalities or acquired conditions, such as polyps and fibroids, that could prevent the embryo from implanting properly.To determine and foretell the likelihood of a genetic defect in the embryo, the couple might also undergo a genetic compatibility test.

Depending on the underlying cause of recurrent pregnancy loss, treatment is advised for women who experience it. A successful pregnancy is highly likely. A doctor should be consulted if a woman has had several miscarriages so they may determine the best course of action to take in order to lower the likelihood of future miscarriages.

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