A gloved hand swabs the inner arm of a person wearing a blue tourniquet, preparing for a blood draw.

Most Essential Screening Tests for Fertility

Fertility screening tests establish where treatment should start. They are advised routinely for anyone having an infertility investigation and cover general health, hormone levels, infection screening and semen analysis. If you have had these tests within the previous six months they will not be repeated, so bring your existing reports to the first consultation.

fertility screening tests
fertility screening tests — Jananam Fertility Centre, Chennai.

Having screening tests done for fertility are essential for the doctor to know where to start treatment. Read on to know what these tests are:

These are tests that are routinely advised for all women who are having an infertility investigation. If you’ve done these tests within the previous six months, they will not be repeated. So, please show us your previous test reports.

1. General Tests (Men and Women)

– Full Blood Count – To check if your Haemoglobin/white cell/platelet count is normal

– FBS/RBS/PPS/HbA1c – To check your blood sugar.

– Urea/Creatinine – To check your kidney functions

– You may be advised to take a Lipid profile if you have PCOS or if you are overweight to see if your cholesterol, triglyceride levels are normal.

2. Infection screening (Men and Women)

– We would screen for Hepatitis B, C, and HIV as a routine

3. Ovarian Reserve Testing (Women)

This is a test to check your ovarian reserve. It is a very important test, it helps us to understand how many eggs are there in your ovary and whether they are increased (PCOS), decreased or satisfactory. This is of immense importance to plan the future course of treatment.

4. Rubella (Women)

Rubella is a virus that causes a common cold. Normally more than 90% of the women have already had this infection and have acquired immunity against it. Women who have never had Rubella virus injection and who get it for the first time while pregnant can have serious consequences to their pregnancy. (The baby can have deafness, blindness or mental retardation). We do IgG testing to confirm immunity. If you’re not immune, we will advise Rubella vaccination and avoiding pregnancy for 1 month after vaccination.

5. Vitamin D (Men and Women)

Much of our population have low vitamin D levels. It plays an important in reproduction. Checking and taking supplements is advisable if the levels are low.

6. Thyroid (Women)

4-5 in 100 women in the reproductive age group will have low thyroid levels. Reduced levels of this hormone can reduce the chances of becoming pregnant and also increase the risk of miscarriage or affect the baby’s IQ and growth. We check thyroid levels and ensure it’s adequately supplemented if deficient. A high level of thyroid hormone will also require correction to ensure a problem-free pregnancy course. Antibodies against the thyroid gland may be present in quite a few women and this suggests that the woman may develop altered thyroid function.

7. Semen Analysis (Men)

This is the most important test to assess whether you have adequate sperm numbers (count), movement (motility) and appearance (morphology). We advise you to do this test after 2-3 days of abstinence-only. Your test results will be discussed by the doctor. You may be advised other blood tests rarely if you have other medical problems.

Which fertility screening tests will I need?

Why are general blood tests included?

Because conditions that affect fertility and pregnancy are often silent. A full blood count, blood sugar, kidney function and thyroid tests identify anaemia, undiagnosed diabetes and thyroid disease, all of which are worth correcting before treatment rather than during it.

Do both partners need testing?

Yes. Male factor contributes to a substantial proportion of cases, and a semen analysis is quick and inexpensive. Investigating only one partner risks spending months looking in the wrong place.

Will my previous test reports be accepted?

Generally yes, if they were done within the previous six months. Bring the actual reports rather than a summary, as the specific values matter. Older results are usually repeated because hormone levels and semen parameters change over time.

What does an ovarian reserve test show?

AMH and antral follicle count together estimate how many eggs remain, which helps predict how the ovaries will respond to stimulation. They indicate quantity rather than quality, and neither predicts natural conception on its own.

Are infection screening tests necessary?

Yes, and they are standard before any assisted reproduction. They protect you, a future pregnancy, and anything stored in the laboratory, and some are a regulatory requirement before treatment can proceed.

How long do the results take?

Most blood tests return within a few days, and a semen analysis is usually available quickly. Imaging of the uterus and tubes is scheduled at a specific point in the cycle, so the full picture typically takes one cycle to assemble.

Related reading

Clinical references

Independent clinical guidance relevant to this topic:

Medically reviewed by Dr. Mangalam — Senior Reproductive Specialist, Jananam Fertility Centre, Chennai.

This article is for general information and is not a substitute for personalised medical advice. Fertility treatment outcomes vary with age, diagnosis and individual circumstances. Please consult a qualified fertility specialist about your own situation. Sex determination and sex selection are prohibited by law in India under the PCPNDT Act, 1994.

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